Prostate Specific Antigen (KLK3) Mouse Monoclonal Antibody [Clone ID: 5A11E9]

CAT#: TA336798

Mouse Monoclonal Kallikrein 3/PSA Antibody (5A11E9)

Product Images

Flow Cytometry: Kallikrein 3/PSA Antibody (5A11E9) TA336798 - Flow cytometric analysis of PC-3 cells using Prostate Specific Antigen mouse mAb (right) and negative control (left).

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  Immunohistochemistry-Paraffin: Kallikrein 3/PSA Antibody (5A11E9) TA336798 - Analysis of paraffin-embedded human prostate tissues using Prostate Specific Antigen mouse mAb with DAB staining.

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  Immunohistochemistry-Paraffin: Kallikrein 3/PSA Antibody (5A11E9) TA336798 - Analysis of paraffin-embedded human prostate carcinoma tissues, showing cytoplasmic localization using Prostate Specific Antigen mouse mAb with DAB staining.

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  Western Blot: Kallikrein 3/PSA Antibody (5A11E9) TA336798 - Analysis against truncated Prostate Specific Antigen recombinant protein.

Specifications

Product Data

• Clone Name: 5A11E9
• Applications: FC, IHC, WB
• Recommended Dilution: Western Blot: 1:500-1:2000, Immunohistochemistry-Paraffin: 1:200-1:1000, Flow Cytometry: 1:200-1:400, ELISA: 1:10000, Immunohistochemistry: 1:10-1:500
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of Prostate Specific Antigen (amino acids 26-251) expressed in E. coli. [UniProt# P07288]
• Formulation: Preservative: 0.05% Sodium Azide. Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Ascites
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: kallikrein related peptidase 3
• Database Link:
  NP_001639
  Entrez Gene 354 Human
  UniProt ID P07288
• Background: Prostate Specific Antigen (PSA, Kallikrein-3, KLK3) is a serine protease that is usually secreted from the prostate gland and presented in seminal plasma. Prostate Specific Antigen functions in the liquefaction of seminal coagulum, through hydrolysis of the high molecular mass seminal vesicle protein. Its substrates includes semenogelin I & II, fibronectin, insulin-like growth factor binding protein 3 (IGBP3), and laminin. Highly expressed by normal and malignant prostate cancer cells, Prostate Specific Antigen has been implicated in the growth, invasion, and metastasis of prostate cancer cells. Therefore, Prostate Specific Antigen is widely used as a diagnostic marker for prostate cancer.
• Synonyms: APS; hK3; KLK2A1; PSA
• Note: This Prostate Specific Antigen (5A11E9) antibody is useful for Western blot, Flow Cytometry, Immunohistochemistry on paraffin-embedded sections and ELISA.

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein
• Protein Pathways: Pathways in cancer, Prostate cancer