Carbonic Anhydrase IX (CA9) Mouse Monoclonal Antibody [Clone ID: 2D3]

CAT#: TA336805

Mouse Monoclonal Carbonic Anhydrase IX/CA9 Antibody (2D3)


USD 424.00

2 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Clone Name 2D3
Applications FC, IHC, WB
Recommended Dilution Flow (Intracellular): 1 ug/mL, Immunocytochemistry/ Immunofluorescence, Western Blot: 1:2000, ELISA: 1:10000, Flow Cytometry: 1:200 - 1:400, Immunohistochemistry: 1:10 - 1:500, Immunohistochemistry-Paraffin: 1:200 - 1:1000, CyTOF-ready
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Purified recombinant fragment of human Carbonic Anhydrase IX expressed in E. coli. [UniProt# Q16790]
Formulation PBS with 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification IgG purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 50 kDa
Gene Name carbonic anhydrase 9
Background Carbonic Anhydrase IX, also known as CA9, is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia. Tissue specificity: Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.
Synonyms CAIX; MN
Note This Carbonic Anhydrase IX (2D3) antibody is useful for Western blot, Flow Cytometry, Immunohistochemistry on paraffin-embedded sections and ELISA.
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Nitrogen metabolism

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.