Hsp60 (HSPD1) Rabbit Polyclonal Antibody

CAT#: TA336825

Rabbit Polyclonal HSP60 Antibody


USD 424.00

5 Days*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution Immunohistochemistry: 1:200, Immunocytochemistry/ Immunofluorescence: 1:1000, Immunohistochemistry-Paraffin: 1:200, Simple Western: 1:5000, Flow (Intracellular), Flow Cytometry, Western Blot: 0.5 ug/mL
Reactivities Human, Mouse, Rat, Hamster, Primate
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide made to an internal region of the human Hsp60 protein (within residues 300-360). [Swiss-Prot P10809]
Formulation PBS with 30% Glycerol, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name heat shock protein family D (Hsp60) member 1
Background Heat shock protein 60 activates T cells and ultimately autoimmune actions and diseases. In gastric cancer, Hsp60 is upregulated in malignant ascites that have been treated, and induces a tumor-specific cytotoxic T lymphocyte response. Enhancing Hsp60 expression is beneficial for protecting bone tissue against osteoblast apoptosis. Hsp60 is highly influenced by dietary intake of antioxidants, and is a prime target for many natural therapies against gut inflammation, preeclampsia, and some low level bacterial infections. Ischemia and reperfusion, as well as hypoxic environments can cause temporary elevations in Hsp60 expression levels.
Synonyms CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HuCHA60; SPG13
Note This Hsp60 antibody is useful for Immunocytochemistry/Immunofluorescence, Western Blot, and IHC-paraffin embedded sections. In Western Blot, a band is seen ~61 kDa representing Hsp60. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways RNA degradation, Type I diabetes mellitus

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.