Collagen I (COL1A1) Rabbit Polyclonal Antibody

CAT#: TA336830

Rabbit Polyclonal Collagen I alpha 1 Antibody


USD 424.00

5 Days*

Size
    • 100 ul

Product Images

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Specifications

Product Data
Applications IHC
Recommended Dilution Immunocytochemistry/ Immunofluorescence: 10-20 ug/ml, Western Blot (Negative), Immunohistochemistry-Paraffin: 1:200, Immunohistochemistry: 1:200
Reactivities Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide made to an internal portion of the human Collagen I protein (between residues 150-200) [UniProt P02452]
Formulation PBS, 30% glycerol, 0.1% Sodium Azide. Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Immunogen affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name collagen type I alpha 1
Background Collagen-1 (also known as collagen alpha, COL1A1, and alpha-1 type I collagen) is the largest component of fibrillar collagen found in cartilage and connective tissues, and synthesizes by fibroblasts, osteoblasts, and odontoblasts. Trimers are formed by combing two alpha one chains and one alpha 2 chain. Mutations of the gene are found in Ehlers-Danlos syndrome, as well as osteogenesis imperfecta. Over 50 mutations have been found in these diseases, including deletions, insertions, splice variants, and substitutions.
Synonyms EDSC; OI1; OI2; OI3; OI4
Note This Collagen 1 antibody is useful for IHC-paraffin embedded sections.
Reference Data
Protein Families Druggable Genome
Protein Pathways ECM-receptor interaction, Focal adhesion

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.