HDAC10 Rabbit Polyclonal Antibody

CAT#: TA336886

Rabbit Polyclonal HDAC10 Antibody

Product Images

Western Blot: HDAC10 Antibody TA336886 - analysis of HDAC-10 in HeLa cells using this antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:250-1:1000
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Recombinant human HDAC-10.
• Formulation: PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Protein G purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: histone deacetylase 10
• Database Link:
  NP_114408
  Entrez Gene 83933 Human
  UniProt ID Q969S8
• Background: A novel class II histone deacetylase, HDAC10 is most similar to HDAC6. Both contain a unique, putative second catalytic domain not found in other HDACs. In HDAC10, however, this domain is not functional. Unlike HDAC6, which is normally a cytoplasmic deacetylase, HDAC10 resides in both the nucleus and cytoplasm. Data suggests that HDAC10 may play roles both in the nucleus, as a transcriptional modulator, and in the cytoplasm in an unidentified role. HDAC10 variants seem present in certain cell lines and tissues that are as of yet not characterized..
• Synonyms: HD10

Reference Data

• Protein Families: Druggable Genome, Transcription Factors