AREB6 (ZEB1) Mouse Monoclonal Antibody [Clone ID: 2A8A6]

CAT#: TA336943

Mouse Monoclonal ZEB1 Antibody (2A8A6)


USD 424.00

5 Days*

Size
    • 100 ul

Frequently bought together (2)
Transient overexpression lysate of zinc finger E-box binding homeobox 1 (ZEB1), transcript variant 2
    • 100 ug

USD 605.00


beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 159.00

Other products for "AREB6"

Specifications

Product Data
Clone Name 2A8A6
Applications FC, IHC
Recommended Dilution Western Blot: 1: 500 - 1:2000, Flow Cytometry: 1:200 - 1:400, Immunocytochemistry/ Immunofluorescence: 1:100, Immunohistochemistry: 1:200 - 1:1000, Immunohistochemistry-Paraffin: 1:200 - 1:1000
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Partial recombinant human ZEB1 (between residues 800-1124) expressed in E. coli [Uniprot P37275]
Formulation PBS, 0.03% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Ammonium sulfate precipitation
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name zinc finger E-box binding homeobox 1
Background ZEB1 (zinc-finger E-box-binding homeobox 1), also known as TCF8 (transcription factor 8), is a delta-EF1/ZFH-1 C2H2-type zinc finger that bears seven C2H2-type zinc fingers and one homeobox DNA-binding domain. ZEB1 is a transcriptional repressor of interleukin-2 (IL-2). Mutations in the ZEB1 gene are associated with posterior corneal dystrophy type 3 (PPC3) a rare disorder characterized by metaplasia and overgrowth of corneal endothelial cells. ZEB1 appears to be critical to epithelial to mesenchymal transitions (EMT) during development and cancer metastasis. As a transcription factor involved in EMT, ZEB1 promotes EMT by repressing genes associated with the epithelial phenotype and activates genes associated with the mesenchymal phenotype.
Synonyms AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3; TCF8; ZFHEP; ZFHX1A
Reference Data
Protein Families Transcription Factors

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.