ABCG5 Mouse Monoclonal Antibody [Clone ID: 1B5E10]

CAT#: TA336947

Mouse Monoclonal ABCG5 Antibody (1B5E10)


USD 424.00

5 Days*

Size
    • 100 ul

Frequently bought together (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 159.00

Other products for "ABCG5"

Specifications

Product Data
Clone Name 1B5E10
Applications FC, IHC, WB
Recommended Dilution Flow Cytometry: 1:200 - 1:400, ELISA: 1:10000, Immunohistochemistry: 1:200 - 1:2000, Western Blot: 1:500 - 1:2000, Immunohistochemistry-Paraffin: 1:200 - 1:2000, ICC/IF (Negative)
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Partial recombinant human ABCG5 (between residues 300-500) expressed in E. coli [UniProt Q9H222].
Formulation PBS, 0.03% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Ammonium sulfate precipitation
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name ATP binding cassette subfamily G member 5
Background ABCG5 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCG5 is a member of the White subfamily. It functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. ABCG5 is expressed in a tissue-specific manner in the liver, colon, and intestine. Mutations in this protein may contribute to sterol accumulation and atheroschlerosis, and they have been observed in patients with sitosterolemia (1).
Synonyms STSL
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways ABC transporters

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.