WNT5A Rabbit Polyclonal Antibody

CAT#: TA337059

Rabbit Polyclonal Wnt-5a Antibody

Product Images

Immunohistochemistry-Paraffin: Wnt-5a Antibody TA337059 - Analysis of Wnt-5a in FFPE human breast tumor using an isotype control (left) and Wnt-5a antibody (right)

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  Western Blot: Wnt-5a Antibody TA337059 - Analysis of Wnt-5a in human heart lysate in the 1) absence, 2) presence of immunizing peptide, 3) mouse and 4) rat heart

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry, Western Blot: 0.5-2 ug/ml, Immunohistochemistry-Paraffin: 5-10 ug/ml, Immunohistochemistry-Frozen
• Reactivities: Human, Mouse, Rat, Bovine, Primate
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide corresponding to amino acids 190-230 of human Wnt5A was used as the immunogen for this antibody, GenBank no NP_003383.2.
• Formulation: PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at -20C. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Protein G purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Wnt family member 5A
• Database Link:
  NP_003383
  Entrez Gene 22418 MouseEntrez Gene 64566 RatEntrez Gene 7474 Human
  UniProt ID P41221
• Background: Wnt5A is a secreted protein found in the extracellular region that belongs to the Wnt family. It is a proto-oncogene that functions in modulating cell fate and behavior during vertebrate development and has an important role in Wnt signaling pathway. It is a glycoprotein that plays an important role in cell communication and development. Wnt5A acts as a ligand for members of the frizzled family of seven transmembrane receptors. It is suspected that Wnt5A is a developmental protein. Wnt5A is a signaling molecule which affects the development of discrete regions of tissues and is likely to signal over only few cell diameters.
• Synonyms: hWNT5A

Reference Data

• Protein Families: Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway
• Protein Pathways: Basal cell carcinoma, Hedgehog signaling pathway, Melanogenesis, Pathways in cancer, Wnt signaling pathway