WNT5A Mouse Monoclonal Antibody [Clone ID: 4M5E4]

CAT#: TA337152

Mouse Monoclonal Wnt-5a Antibody (4M5E4)

Product Images

Immunohistochemistry-Paraffin: Wnt5a Antibody (4M5E4) TA337152 - Staining of human breast tumor tissue probed with Wnt5A antibody at 5 ug/ml.

Specifications

Product Data

• Clone Name: 4M5E4
• Applications: IHC
• Recommended Dilution: IHC-P: 5-10ug/ml
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a, kappa
• Clonality: Monoclonal
• Immunogen: A portion of the human Wnt5A protein was used as the immunogen for this antibody.
• Formulation: PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Protein G purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Wnt family member 5A
• Database Link:
  NP_003383
  Entrez Gene 7474 Human
  UniProt ID P41221
• Background: Wnt5A is a secreted protein found in the extracellular region that belongs to the Wnt family. It is a proto-oncogene that functions in modulating cell fate and behavior during vertebrate development and has an important role in Wnt signaling pathway. It is a glycoprotein that plays an important role in cell communication and development. Wnt5A acts as a ligand for members of the frizzled family of seven transmembrane receptors. It is suspected that Wnt5A is a developmental protein. Wnt5A is a signaling molecule which affects the development of discrete regions of tissues and is likely to signal over only few cell diameters.
• Synonyms: hWNT5A

Reference Data

• Protein Families: Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway
• Protein Pathways: Basal cell carcinoma, Hedgehog signaling pathway, Melanogenesis, Pathways in cancer, Wnt signaling pathway