IL17F Mouse Monoclonal Antibody [Clone ID: 4H1629]

CAT#: TA337155

Mouse Monoclonal IL-17F Antibody (4H1629)

Product Images

Western Blot: IL17F Antibody (4H1629) TA337155 - WB analysis on full-length recombinant IL-17F proteins of (1) Human, (2) Mouse and (3) Rat using IL17F antibody (clone 4H1629) at a concentration of 0.5 ug/ml. Note: This antibody did not detect the mouse

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  Immunohistochemistry-Paraffin: IL17F Antibody (4H1629) TA337155 - IHC-P analysis of IL-17F in formalin-fixed paraffin-embedded human colon tissue using an isotype control (top left) and IL17F antibody (bottom left and right) at 5 ug/ml concentration.

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  Immunohistochemistry-Paraffin: IL17F Antibody (4H1629) TA337155 - IHC-P detection IL17F protein in a tissue section of human lymph node cancer using IL17F antibody (clone 4H1629) at a concentration of 5 ug/ml.

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  Immunohistochemistry-Paraffin: IL17F Antibody (4H1629) TA337155 - IHC-P detection IL17F protein in a tissue section of human stomach cancer using IL17F antibody (clone 4H1629) at a concentration of 5 ug/ml. Diffused cytoplasmic staining was observed in

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  Immunohistochemistry-Paraffin: IL17F Antibody (4H1629) TA337155 - IHC-P detection IL17F protein in a tissue section of normal human stomach using IL17F antibody (clone 4H1629) at a concentration of 5 ug/ml. Cytoplasmic expression was observed all over t

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Specifications

Product Data

• Clone Name: 4H1629
• Applications: IHC, WB
• Recommended Dilution: WB: 0.5-2ug/ml~, IHC: 5 ug/ml, IHC-P: 5 ug/ml
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Immunogen: Full-length recombinant MRkIPkVGHT FFQkPESCPP VPGGSMkLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGkEDISMN SVPIQQETLV VRRkHQGCSV SFQLEkVLVT VGCTCVTPVI HHVQ
• Formulation: PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Protein G purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interleukin 17F
• Database Link:
  NP_443104
  Entrez Gene 112744 Human
  UniProt ID Q96PD4
• Background: Interleukin 17 (IL-17) is a pro-inflammatory cytokine produced by a subset of T helper cells that develops distinct from the Th1- and Th2- cell differentiation pathways. IL-17, also known as CTLA-8, stimulates induction of other pro-inflammatory cytokines TNF alpha, IL-1 beta, IL-6, and IL-8, and reports strongly suggest the involvement of IL-17 in several chronic inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis. TGF-Beta (differentiation) and IL-23 (expansion) are required for induction and maintenance of Th17 (IL-17 producing) cells, which in turn induce the other pro-inflammatory cytokines. IL-17 (~32kDa) protein is produced and exists as a homo-dimer, has homology to a herpes virus early protein, is one of the six members (IL-17A-F) of this cytokine family, and is well characterzed and highly expressed by activated effector memory T cells.
• Synonyms: CANDF6; IL-17F; ML-1; ML1

Reference Data

• Protein Families: Druggable Genome, Secreted Protein