CCR1 Rabbit Polyclonal Antibody

CAT#: TA337191

Rabbit Polyclonal CCR1 Antibody

Product Images

Immunohistochemistry-Paraffin: CCR1 Antibody TA337191 - Analysis of spleen (lymphocytes) using this antibody at 5 ug/ ml.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 1:10-1:500, IHC-P: 5 ug/ml
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to the 2nd extracellular domain of human C-C Chemokine Receptor 1 (CCR1)
• Formulation: PBS, 30% glycerol, 0.1% Sodium Azide. Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: C-C motif chemokine receptor 1
• Database Link:
  NP_001286
  Entrez Gene 1230 Human
  UniProt ID P32246
• Background: CCR1, a Chemokine Receptor, affects stem cell proliferation and mediates systemic inflammatory responses. This receptor is stimulated by the beta chemokines RANTES, MCP-1, and MIP-1 alpha. Disruption of CCR1 enhances protection from pulmonary inflammation and reduces the development of respiratory distress syndrome in rat. CCR1 is widely expressed, particularly in hematopoietic cells from blood, vessels, and bone marrow. This receptor has also been reported to be expressed in lung, brain, placenta, heart, skeletal muscle, and kidney. ESTs have been isolated from blood, kidney, liver/spleen, lung, placenta, uterus, and vessel libraries.
• Synonyms: CD191; CKR-1; CKR1; CMKBR1; HM145; MIP1aR; SCYAR1

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction