TXNRD3 Rabbit Polyclonal Antibody

CAT#: TA337942

Rabbit Polyclonal Anti-TXNRD3 Antibody

Product Images

WB Suggested Anti-TXNRD3 Antibody; Titration: 1.0 ug/ml; Positive Control: OVCAR-3 Whole Cell

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-TXNRD3 antibody is: synthetic peptide directed towards the N-terminal region of Human TXNRD3. Synthetic peptide located within the following region: LSPPGRRARLSSPGPSRSSEAREELRRHLVGLIERSRVVIFSKSYCPHST
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 70 kDa
• Gene Name: thioredoxin reductase 3
• Database Link:
  NP_443115
  Entrez Gene 114112 Human
  UniProt ID Q86VQ6
• Background: This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: TGR; TR2; TRXR3
• Note: Immunogen Sequence Homology: Human: 100%; Mouse: 86%; Rabbit: 86%