delta 2 Catenin (CTNND2) Rabbit Polyclonal Antibody

CAT#: TA338276

Rabbit Polyclonal Anti-CTNND2 Antibody

Product Images

WB Suggested Anti-CTNND2 Antibody; Titration: 1.0 ug/ml; Positive Control: 721_B Whole Cell

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-CTNND2 antibody is: synthetic peptide directed towards the C-terminal region of Human CTNND2. Synthetic peptide located within the following region: PNNRSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKDAMTA
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 133 kDa
• Gene Name: catenin delta 2
• Database Link:
  NP_001323
  Entrez Gene 1501 Human
  UniProt ID Q9UQB3
• Background: This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome.
• Synonyms: GT24; NPRAP
• Note: Immunogen Sequence Homology: Human: 100%; Dog: 93%; Pig: 93%; Horse: 93%; Bovine: 93%; Rabbit: 93%; Guinea pig: 93%; Zebrafish: 92%; Mouse: 79%

Reference Data

• Protein Families: Druggable Genome