Bone Sialoprotein (IBSP) Rabbit Polyclonal Antibody

CAT#: TA341700

Rabbit Polyclonal Anti-IBSP Antibody

Product Images

WB Suggested Anti-IBSP Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysate

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-IBSP antibody: synthetic peptide directed towards the N terminal of human IBSP. Synthetic peptide located within the following region: SATTLGYGEDATPGTGYTGLAAIQLPKKAGDITNKATKEKESDEEEEEEE
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 35 kDa
• Gene Name: integrin binding sialoprotein
• Database Link:
  NP_004958
  Entrez Gene 3381 Human
  UniProt ID P21815
• Background: The protein encoded byThis gene is a major structural protein ofThe bone matrix. It constitutes approximately 12% ofThe noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts.The only extraskeletal site of its synthesis isThe trophoblast.This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizesThe vitronectin receptor. [provided by RefSeq, Jul 2008]
• Synonyms: BNSP; BSP; BSP-II; SP-II
• Note: Immunogen Sequence Homology: Human: 100%; Dog: 79%

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: ECM-receptor interaction, Focal adhesion