Calcitonin receptor (CALCR) Rabbit Polyclonal Antibody

CAT#: TA342679

Rabbit Polyclonal Anti-CALCR Antibody

Product Images

WB Suggested Anti-CALCR Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human kidney

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-CALCR antibody: synthetic peptide directed towards the C terminal of human CALCR. Synthetic peptide located within the following region: NQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEII
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 52 kDa
• Gene Name: calcitonin receptor
• Database Link:
  NP_001733
  Entrez Gene 799 Human
  UniProt ID P30988
• Background: This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.
• Synonyms: CRT; CT-R; CTR; CTR1
• Note: Immunogen Sequence Homology: Human: 100%; Dog: 79%; Pig: 79%; Guinea pig: 79%; Bovine

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction