SIAH2 Rabbit Polyclonal Antibody

CAT#: TA344469

Rabbit Polyclonal Anti-SIAH2 Antibody - N-terminal region

Product Images

Lanes: 1: 50ug HEK293T lysate, 2: 50ug A549 lysate; Primary Antibody Dilution: 1:1000; Secondary Antibody: Anti-rabbit-HRP; Secondary Antibody Dilution: 1:5000; Gene Name: SIAH2; Submitted by: Peter Brand & Dr. Oliver Krammer, Institute for Biotechnology

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  WB Suggested Anti-SIAH2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Hela cell lysate

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  Host: Rabbit; Target Name: SIAH2; Sample Tissue: HepG2; Antibody Dilution: 1.0 ug/ml; SIAH2 is supported by BioGPS gene expression data to be expressed in HepG2

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  Host: Rabbit; Target Name: SIAH2; Sample Tissue: MCF7; Antibody Dilution: 1.0 ug/ml; SIAH2 is supported by BioGPS gene expression data to be expressed in MCF7

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  Host: Rabbit; Target Name: SIAH2; Sample Tissue: Hela; Lane A: Primary Antibody; Lane B: Primary Antibody + Blocking Peptide ; Primary Antibody Concentration:1 ug/ml; Peptide Concentration: 5ug/ml; Lysate Quantity: 25ug/lane/lane; Gel Concentration: 0.12

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Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-SIAH2 antibody: synthetic peptide directed towards the N terminal of human SIAH2. Synthetic peptide located within the following region: SRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAA
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 34 kDa
• Gene Name: siah E3 ubiquitin protein ligase 2
• Database Link:
  NP_005058
  Entrez Gene 6478 Human
  UniProt ID O43255
• Background: SIAH2 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Synonyms: hSiah2
• Note: Immunogen Sequence Homology: Human: 100%; Pig: 93%; Bovine: 93%; Dog: 92%; Rat: 80%; Mouse: 80%

Reference Data

• Protein Families: Druggable Genome, Transcription Factors