MSH6 Rabbit Polyclonal Antibody

CAT#: TA346016

Rabbit Polyclonal Anti-MSH6 Antibody

Product Images

WB Suggested Anti-MSH6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: THP-1 cell lysate

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  MSH6 antibody - N-terminal region validated by WB using Human B cells and Mouse B cells and Chicken B Cells at 0.8 ug/ml.

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  Sample Type: Human Tonsil TissuePrimary; Dilution: 1 ug/mL

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  Sample Type: Human Colon CancerPrimary Dilution: 1 ug/mL

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB, IHC
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-MSH6 antibody: synthetic peptide directed towards the N terminal of human MSH6. Synthetic peptide located within the following region: ISDSESDIGGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNSPVKVARKR
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 153 kDa
• Gene Name: mutS homolog 6
• Database Link:
  NP_000170
  Entrez Gene 17688 MouseEntrez Gene 2956 Human
  UniProt ID P52701
• Background: This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs.
• Synonyms: GTBP; GTMBP; HNPCC5; HSAP; p160
• Note: Immunogen Sequence Homology: Pig: 100%; Human: 100%; Guinea pig: 100%; Dog: 93%; Rat: 93%; Horse: 93%; Bovine: 93%; Rabbit: 93%; Mouse: 86%

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Colorectal cancer, Mismatch repair, Pathways in cancer