Cytokeratin 1 (KRT1) Rabbit Polyclonal Antibody

CAT#: TA346426

Rabbit Polyclonal Anti-KRT1 Antibody

Product Images

WB Suggested Anti-KRT1 Antibody; Titration: 1 ug/ml; Positive Control: 293T cells lysate

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  Rabbit Anti-KRT1 Antibody; Paraffin Embedded Tissue: Human Skin; Antibody Concentration: 1.25-2.5 ug/ml

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB, IHC
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-KRT1 antibody: synthetic peptide directed towards the middle region of human KRT1. Synthetic peptide located within the following region: GSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKS
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 66 kDa
• Gene Name: keratin 1
• Database Link:
  NP_006112
  Entrez Gene 3848 Human
  UniProt ID P04264
• Background: KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Synonyms: CK1; EHK; EHK1; EPPK; K1; KRT1A; NEPPK
• Note: Immunogen Sequence Homology: Human: 100%; Rat: 93%; Rabbit: 93%; Dog: 86%

Reference Data

• Protein Families: Druggable Genome