ATP citrate lyase (ACLY) Mouse Monoclonal Antibody [Clone ID: 3D9-E9-H8]

CAT#: TA346872

Mouse Monoclonal ATP-Citrate Lyase (C-terminus) Antibody


USD 380.00

4 Weeks*

Size
    • 100 ul

Product Images

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Specifications

Product Data
Clone Name 3D9-E9-H8
Applications FC, IF, WB
Recommended Dilution WB: 1:1000, IF: 1:150, FC: 1:100
Reactivities Human, Monkey, Mouse
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen The immunogen for ACLY antibody: purified recombinant human ATP-Citrate Lyase protein fragments expressed in E.coli.
Formulation Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
Purification Affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 120 kDa
Gene Name ATP citrate lyase
Background ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms ACL; ATPCL; CLATP
Reference Data
Protein Families Druggable Genome
Protein Pathways Citrate cycle (TCA cycle), Metabolic pathways

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.