cIAP2 (BIRC3) Mouse Monoclonal Antibody [Clone ID: 1F12-E5-G12]

CAT#: TA346895S

Mouse Monoclonal cIAP2 Antibody

Specifications

Product Data

• Clone Name: 1F12-E5-G12
• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human, Monkey
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for BIRC3 antibody: purified recombinant human c-IAP2 protein fragments expressed in E.coli
• Formulation: ascites
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 72 kDa
• Gene Name: baculoviral IAP repeat containing 3
• Database Link:
  NP_001156
  Entrez Gene 330 Human
  UniProt ID Q13489
• Background: This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases.The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione,a potent inducer of free radicals.It contains 3 baculovirus IAP repeats and a ring finger domain.Transcript variants encoding the same isoform have been identified. [provided by RefSeq,Aug 2011]
• Synonyms: AIP1; API2; c-IAP2; CIAP2; HAIP1; HIAP1; MALT2; MIHC; RNF49

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Apoptosis, Focal adhesion, NOD-like receptor signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis