HP1 gamma (CBX3) Mouse Monoclonal Antibody [Clone ID: 5G10-F7-A12]

CAT#: TA346904S

Mouse Monoclonal HP1-gamma Antibody


USD 85.00

2 Weeks*

Size
    • 20 ul

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Specifications

Product Data
Clone Name 5G10-F7-A12
Applications IF, IHC, IP, WB
Recommended Dilution WB: 1:1000, IF: 1:200
Reactivities Human, Monkey, Mouse, Hamster, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen The immunogen for CBX3 antibody: purified recombinant human HP1-gamma protein fragments expressed in E.coli.
Formulation Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Purification Affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 22 kDa
Gene Name chromobox 3
Background At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene. [provided by RefSeq, Mar 2011]
Synonyms HECH; HP1-GAMMA; HP1Hs-gamma
Reference Data
Protein Families Druggable Genome, Transcription Factors

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.