HP1 alpha (CBX5) Mouse Monoclonal Antibody [Clone ID: 3G2-H10-A6]

CAT#: TA346905

Mouse Monoclonal HP1 alpha Antibody


USD 380.00

4 Weeks*

Size
    • 100 ul

Product Images

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Specifications

Product Data
Clone Name 3G2-H10-A6
Applications IF, IHC, WB
Recommended Dilution WB: 1:1000, IF: 1:300
Reactivities Human, Mouse
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen The immunogen for CBX5 antibody: purified recombinant human HP1 alpha protein fragments expressed in E.coli.
Formulation Purified mouse monoclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
Purification Affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 26 kDa
Gene Name chromobox 5
Background This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Synonyms HEL25; HP1; HP1A
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.