c Fos (FOS) Mouse Monoclonal Antibody [Clone ID: 7D6-A9-D4]

CAT#: TA346914

Mouse Monoclonal c-Fos Antibody

Specifications

Product Data

• Clone Name: 7D6-A9-D4
• Applications: WB
• Recommended Dilution: WB: 1:500
• Reactivities: Human, Rat, Monkey
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for C-FOS antibody: purified recombinant human FOS protein fragments expressed in E.coli.
• Formulation: Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 62 kDa
• Gene Name: Fos proto-oncogene, AP-1 transcription factor subunit
• Database Link:
  NP_005243
  Entrez Gene 314322 RatEntrez Gene 702077 MonkeyEntrez Gene 2353 Human
  UniProt ID P01100
• Background: The Fos gene family consists of 4 members: FOS,FOSB,FOSL1,and FOSL2.These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family,thereby forming the transcription factor complex AP-1 As such,the FOS proteins have been implicated as regulators of cell proliferation,differentiation, and transformation.In some cases,expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq,Jul 2008]
• Synonyms: AP-1; C-FOS; p55

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: B cell receptor signaling pathway, Colorectal cancer, MAPK signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway