TFIIB (GTF2B) Mouse Monoclonal Antibody [Clone ID: 2F6-A3]

CAT#: TA346956

Mouse Monoclonal TFIIB Antibody

Specifications

Product Data

• Clone Name: 2F6-A3
• Applications: WB
• Recommended Dilution: WB: 1:500
• Reactivities: Human, Monkey, Mouse
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: The immunogen for GTF2B antibody: purified recombinant human TFIIB protein fragments expressed in E.coli.
• Formulation: ascites
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 34 kDa
• Gene Name: general transcription factor IIB
• Database Link:
  NP_001505
  Entrez Gene 229906 MouseEntrez Gene 2959 Human
  UniProt ID Q00403
• Background: GTF2B is one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.
• Synonyms: TF2B; TFIIB

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Basal transcription factors