IKK beta (IKBKB) Mouse Monoclonal Antibody [Clone ID: 1C3-B11-B12]

CAT#: TA346977

Mouse Monoclonal IKKβ Antibody

Product Images

Western blot detection of IKKβ in THP-1 and PC12 cell lysates using IKKβ mouse mAb (1:500 diluted).Predicted band size:87KDa.Observed band size:87KDa.

Specifications

Product Data

• Clone Name: 1C3-B11-B12
• Applications: WB
• Recommended Dilution: WB: 1:500
• Reactivities: Human, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for IKBKB antibody: purified recombinant human IKKβ protein fragments expressed in E.coli.
• Formulation: Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 87 kDa
• Gene Name: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
• Database Link:
  NP_001547
  Entrez Gene 84351 RatEntrez Gene 3551 Human
  UniProt ID O14920
• Background: The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.
• Synonyms: IKK-beta; IKK2; IKKB; IMD15; NFKBIKB

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transcription Factors
• Protein Pathways: Acute myeloid leukemia, Adipocytokine signaling pathway, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, Insulin signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Pancreatic cancer, Pathways in cancer, Prostate cancer, RIG-I-like receptor signaling pathway, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus