CD61 (ITGB3) Mouse Monoclonal Antibody [Clone ID: 3C12-G2-E4-H9]

CAT#: TA346981

Mouse Monoclonal Integrin beta 3(N-terminus) Antibody

Specifications

Product Data

• Clone Name: 3C12-G2-E4-H9
• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for ITGB3 antibody: purified recombinant human Integrin beta 3(N-terminus) protein fragments expressed in E.coli.
• Formulation: Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 110 kDa
• Gene Name: integrin subunit beta 3
• Database Link:
  NP_000203
  Entrez Gene 3690 Human
  UniProt ID P05106
• Background: The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
• Synonyms: BDPLT2; BDPLT16; CD61; GP3A; GPIIIa; GT

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton