Klf4 Mouse Monoclonal Antibody [Clone ID: 3B3-B11-E6]
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Specifications
Product Data | |
Clone Name | 3B3-B11-E6 |
Applications | WB |
Recommended Dilution | WB: 1:1000 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | The immunogen for KLF4 antibody: purified recombinant mouse KLF4 protein fragments expressed in E.coli. |
Formulation | ascites |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 55/65 kDa |
Gene Name | Kruppel-like factor 4 (gut) |
Database Link | |
Background | Transcription factor; can act both as activator and as repressor.Binds the 5'-CACCC-3' core sequence.Binds to the promoter region of its own gene and can activate its own transcription.Regulates the expression of key transcription factors during embryonic development.Plays an important role in maintaining embryonic stem cells,and in preventing their differentiation.Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface.Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.Contributes to the down-regulation of p53/TP53 transcription. |
Synonyms | EZF; GKLF |
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