PKM2 (PKM) Mouse Monoclonal Antibody [Clone ID: 1F2-F4-H11]

CAT#: TA347018

Mouse Monoclonal PKM2 Antibody


USD 380.00

4 Weeks*

Size
    • 100 ul

Product Images

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Specifications

Product Data
Clone Name 1F2-F4-H11
Applications IF, IP, WB
Recommended Dilution WB: 1:1000
Reactivities Human, Monkey
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen The immunogen for PKM2 antibody: purified recombinant human PKM2 protein fragments expressed in E.coli.
Formulation PBS(pH 7.4) containing with 0.03% Proclin300 and 50% glycerol.
Purification Affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 60 kDa
Gene Name pyruvate kinase, muscle
Background This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.
Synonyms CTHBP; HEL-S-30; OIP3; PK3; PKM2; TCB; THBP1
Reference Data
Protein Families Druggable Genome
Protein Pathways Glycolysis / Gluconeogenesis, Metabolic pathways, Purine metabolism, Pyruvate metabolism, Type II diabetes mellitus

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.