PPAR gamma (PPARG) Mouse Monoclonal Antibody [Clone ID: 1G7-G4-G12]

CAT#: TA347020

Mouse Monoclonal PPAR gamma (C-terminus) Antibody

Product Images

Western blot detection of PPAR gamma (C-terminus) in 3T3-L1 and Mouse Lung cell lysates using PPAR gamma (C-terminus) mouse mAb (1:1000 diluted).Predicted band size:54KDa.Observed band size:54KD.

Specifications

Product Data

• Clone Name: 1G7-G4-G12
• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Mouse
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for PPARG antibody: purified recombinant human PPAR gamma (C-terminus) protein fragments expressed in E.coli.
• Formulation: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 54 kDa
• Gene Name: peroxisome proliferator activated receptor gamma
• Database Link:
  NP_619725
  Entrez Gene 19016 Mouse
  UniProt ID P37231
• Background: This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in thepathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
• Synonyms: CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Protein Pathways: Huntington's disease, Pathways in cancer, PPAR signaling pathway, Thyroid cancer