DNA PKcs (PRKDC) Mouse Monoclonal Antibody [Clone ID: 8D3-B12-F11]

CAT#: TA347029

Mouse Monoclonal DNA-PKcs Antibody

Specifications

Product Data

• Clone Name: 8D3-B12-F11
• Applications: IF, IP, WB
• Recommended Dilution: WB: 1:1000, IF: 1:200
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: The immunogen for PRKDC antibody: purified recombinant human DNA-PKcs protein fragments expressed in E.coli
• Formulation: Purified mouse monoclonal in PBS(pH 7.4)containing with 0.02% sodium azide,50% glycerol.
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 450 kDa
• Gene Name: protein kinase, DNA-activated, catalytic polypeptide
• Database Link:
  NP_008835
  Entrez Gene 5591 Human
  UniProt ID P78527
• Background: This gene encodes the catalytic subunit of the DNA-dependent protein kinase(DNA-PK).It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination.The protein encoded is a member of the PI3/PI4-kinase family. [provided by RefSeq,Jul 2010]
• Synonyms: DNA-PKcs; DNAPK; DNPK1; HYRC; HYRC1; IMD26; p350; XRCC7

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Cell cycle, Non-homologous end-joining