RPA34 (RPA2) Mouse Monoclonal Antibody [Clone ID: 3E7-B5-F2]

CAT#: TA347041

Mouse Monoclonal RPA32/RPA2 Antibody


USD 380.00

4 Weeks*

Size
    • 100 ul

Product Images

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Specifications

Product Data
Clone Name 3E7-B5-F2
Applications IF, IP, WB
Recommended Dilution WB: 1:2000, IF: 1:200
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen The immunogen for RPA2 antibody: purified recombinant human RPA32/RPA2 protein fragments expressed in E.coli.
Formulation Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Purification Affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 32 kDa
Gene Name replication protein A2
Background Required for DNA recombination,repair and replication.The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.Required for the efficient recruitment of the DNA double-strand break repair factor RAD51 to chromatin in response to DNA damage.Functions as component of the alternative replication protein A complex (aRPA).aRPA binds single-stranded DNA and probably plays a role in DNA repair;it does not support chromosomal DNA replication and cell cycle progression through S-phase.In vitro,aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC),the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
Synonyms REPA2; RP-A p32; RP-A p34; RPA32
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways DNA replication, Homologous recombination, Mismatch repair, Nucleotide excision repair

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.