RPA70 (RPA1) Mouse Monoclonal Antibody [Clone ID: 8C3-D12-H10]

CAT#: TA347042

Mouse Monoclonal RPA70 Antibody


USD 380.00

2 Weeks*

Size
    • 100 ul

Product Images

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Specifications

Product Data
Clone Name 8C3-D12-H10
Applications IF, IP, WB
Recommended Dilution WB: 1:1000, IF: 1:100
Reactivities Human, Monkey, Mouse, Rat
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen The immunogen for RPA70 antibody: purified recombinant human RPA70 protein fragments expressed in E.coli.
Formulation Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Purification Affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 70 kDa
Gene Name replication protein A1
Background Plays an essential role in several cellular processes in DNA metabolism including replication,recombination and DNA repair.Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing.Functions as component of the alternative replication protein A complex (aRPA).aRPA binds single-stranded DNA and probably plays a role in DNA repair;it does not support chromosomal DNA replication and cell cycle progression through S-phase.In vitro,aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC),the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
Synonyms HSSB; MST075; REPA1; RF-A; RP-A; RPA70
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways DNA replication, Homologous recombination, Mismatch repair, Nucleotide excision repair

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.