SIRT6 Mouse Monoclonal Antibody [Clone ID: 1B5-G10-H9]

CAT#: TA347046

Mouse Monoclonal SIRT6 Antibody

Product Images

Western blot analysis of extracts from CHO-K1 cells, transfected with pcDNA3.1-FLAG vector (A) or transfected with pcDNA3.1-FLAG-SIRT6 construct (B), using SIRT6 mouse mAb (1:500 diluted).

Specifications

Product Data

• Clone Name: 1B5-G10-H9
• Applications: WB
• Recommended Dilution: WB: 1:500
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for SIRT6 antibody: purified recombinant human SIRT6 protein fragments expressed in E.coli.
• Formulation: Purified mouse monoclonal in PBS(pH 7.4)containing with 0.02% sodium azide,50% glycerol.
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 39 kDa
• Gene Name: sirtuin 6
• Database Link:
  NP_057623
  Entrez Gene 51548 Human
  UniProt ID Q8N6T7
• Background: This gene encodes a member of the sirtuin family of proteins,homologs to the yeast Sir2 protein.Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes.The functions of human sirtuins have not yet been determined;however,yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA.Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.The protein encoded by this gene is included in class IV of the sirtuin family.Alternative splicing results in multiple transcript variants. [provided by RefSeq,Jul 2010]
• Synonyms: SIR2L6

Reference Data

• Protein Families: Druggable Genome, Transcription Factors