Sox2 Mouse Monoclonal Antibody [Clone ID: 2A10-F11-F12]

CAT#: TA347056

Mouse Monoclonal Sox2 Antibody

Product Images

Western blot detection of Sox2 in F9 cell lysates using Sox2 mouse mAb (1:1000 diluted).Predicted band size:35KDa.Observed band size:35KDa.

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  Western blot detection of Sox2 in mES cell lysates using Sox2 antibody (1:1000 diluted).Predicted band size:35KDa, Observed band size:35KDa.

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  Immunocytochemistry of COS7 cells using anti-Sox2 mouse mAb diluted 1:150.

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  Flow Cytometry analysis of F9 cells stained with Sox2 (red, 1/100 dilution), followed by FITC-conjugated goat anti-mouse IgG. Blue line histogram represents the isotype control, normal mouse IgG.

Specifications

Product Data

• Clone Name: 2A10-F11-F12
• Applications: FC, IF, WB
• Recommended Dilution: WB: 1:1000, IF: 1:150
• Reactivities: Mouse
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: The immunogen for Sox2 antibody: purified recombinant mouse Sox2 protein fragments expressed in E.coli
• Formulation: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 35 kDa
• Gene Name: SRY (sex determining region Y)-box 2
• Database Link:
  NP_035573
  Entrez Gene 20674 Mouse
  UniProt ID P48432
• Background: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1,FGF4,UTF1 and ZFP206 by similarity.Critical for early embryogenesis and for embryonic stem cell pluripotency.May function as a switch in neuronal development.Downstream SRRT target that mediates the promotion of neural stem cell self-renewal by similarity.Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation by similarity.
• Synonyms: ANOP3; MCOPS3; MGC2413