PGP9.5 (UCHL1) Mouse Monoclonal Antibody [Clone ID: 7B8-G5-B8]
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Specifications
Product Data | |
Clone Name | 7B8-G5-B8 |
Applications | IF, WB |
Recommended Dilution | WB: 1:1000, IF: 1:300 |
Reactivities | Human, Monkey |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | The immunogen for UCHL1 antibody: purified recombinant human UCHL1 / PGP9.5 protein fragments expressed in E.coli. |
Formulation | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50% glycerol |
Purification | Affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 25 kDa |
Gene Name | ubiquitin C-terminal hydrolase L1 |
Database Link | |
Background | The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease. |
Synonyms | HEL-117; NDGOA; PARK5; PGP 9.5; PGP9.5; PGP95; Uch-L1 |
Reference Data | |
Protein Families | Druggable Genome, Protease |
Protein Pathways | Parkinson's disease |
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