UHRF1 Mouse Monoclonal Antibody [Clone ID: 1H9-D3-E11]

CAT#: TA347069

Mouse Monoclonal UHRF1 (N-terminus) Antibody

Specifications

Product Data

• Clone Name: 1H9-D3-E11
• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human, Mouse
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: The immunogen for UHRF1 antibody: purified recombinant human UHRF1 protein fragments expressed in E.coil.
• Formulation: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 90 kDa
• Gene Name: ubiquitin like with PHD and ring finger domains 1
• Database Link:
  NP_037414
  Entrez Gene 18140 MouseEntrez Gene 29128 Human
  UniProt ID Q96T88
• Background: This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: hNP95; hUHRF1; huNp95; ICBP90; Np95; RNF106
• Note: Detects ~ 38kDa.

Reference Data

• Protein Families: Druggable Genome, Transcription Factors