ASH2L Rabbit Polyclonal Antibody

CAT#: TA347081

Rabbit Polyclonal ASH2 Antibody


USD 358.00

5 Days*

Size
    • 50 ug

Product Images

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Specifications

Product Data
Applications WB
Recommended Dilution Western blotting (1:1,000)
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The immunogen for anti-ASH2 antibody: human Ash2 (absent, small, or homeotic 2), using a recombinant protein.
Concentration lot specific
Purification Protein G purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name ASH2 like histone lysine methyltransferase complex subunit
Background ASH2 (UniProtKB/Swiss-Prot entry Q9UBL3) is a component of the SET1/ASH2 histone methyltransferase (HMT) complex. This complex specifically methylates K4 of histone H3, thereby activating transcription. Methylation of K4 is blocked by premethylation of the neighboring K9, a repressor of transcription. This indicates that the SET1/ASH2 HMT complex mediates the crosstalk between K9 methylation and K4 methylation. ASH2 plays a role in hematopoiesis and may be associated with some kinds of leukemia.
Synonyms ASH2; ASH2L1; ASH2L2; Bre2
Reference Data
Protein Families Druggable Genome, Transcription Factors

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.