H3FA (HIST1H3A) Mouse Monoclonal Antibody

CAT#: TA347151

Mouse Monoclonal H3K4me2 Antibody


USD 450.00

5 Days*

Size
    • 50 ug

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Specifications

Product Data
Applications Assay, ELISA, IF, WB
Recommended Dilution ChIP (1 µg/ChIP); ELISA (1:5,000); Western blotting (1:1,000); Immunofluoresence (1:500)
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen The immunogen for anti-H3K4me2 antibody: histone H3, dimethylated at lysine 4 (H3K4me2), using a KLH-conjugated synthetic peptide
Concentration lot specific
Purification Protein A purified monoclonal antibody in PBS containing 0.05% azide.
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name histone cluster 1, H3a
Background Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called "histone code". Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases.
Synonyms A; H3; H3FA
Reference Data
Protein Pathways Systemic lupus erythematosus

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.