PADI4 Rabbit Polyclonal Antibody

CAT#: TA347254

Rabbit Polyclonal PADI4 Antibody


USD 358.00

5 Days*

Size
    • 100 ul

Product Images

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Specifications

Product Data
Applications ELISA, WB
Recommended Dilution ELISA (1:1,000-1:5,000); Western blotting (1:1,000)
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The immunogen for anti-PADI4 antibody: human PADI4 (Protein-arginine deiminase type-4), using a KLH-conjugated synthetic peptide containing a sequence from the N-terminus.of the protein.
Concentration lot specific
Purification Whole antiserum from rabbit containing 0.05% azide.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name peptidyl arginine deiminase 4
Background Protein arginine deiminases catalyse the conversion of arginine residues in proteins to citrulline. PADI4 (UniProt/Swiss-Prot entry Q9UM07) catalyses the citrullination-deimination of Arg-8 and Arg-17 from histone H3 and Arg-3 from histone H4. This prevents their methylation by CARM1 and HRMT1L2/PRMT1, thereby repressing transcription. PADI4 also citrullinates EP300/P300 at 'Arg-2142', which favours its interaction with NCOA2/GRIP.
Synonyms PAD; PAD4; PADI5; PDI4; PDI5
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.