PADI4 Rabbit Polyclonal Antibody
Frequently bought together (3)
Recombinant protein of human peptidyl arginine deiminase, type IV (PADI4)
USD 823.00
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Specifications
Product Data | |
Applications | ELISA, WB |
Recommended Dilution | ELISA (1:1,000-1:5,000); Western blotting (1:1,000) |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-PADI4 antibody: human PADI4 (Protein-arginine deiminase type-4), using a KLH-conjugated synthetic peptide containing a sequence from the N-terminus.of the protein. |
Concentration | lot specific |
Purification | Whole antiserum from rabbit containing 0.05% azide. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | peptidyl arginine deiminase 4 |
Database Link | |
Background | Protein arginine deiminases catalyse the conversion of arginine residues in proteins to citrulline. PADI4 (UniProt/Swiss-Prot entry Q9UM07) catalyses the citrullination-deimination of Arg-8 and Arg-17 from histone H3 and Arg-3 from histone H4. This prevents their methylation by CARM1 and HRMT1L2/PRMT1, thereby repressing transcription. PADI4 also citrullinates EP300/P300 at 'Arg-2142', which favours its interaction with NCOA2/GRIP. |
Synonyms | PAD; PAD4; PADI5; PDI4; PDI5 |
Reference Data |
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