SETD7 Rabbit Polyclonal Antibody

CAT#: TA347286

Rabbit Polyclonal Set9 Antibody

Product Images

WB was performed on nuclear extracts from HeLa cells (HeLa NE, 20 ug) using the antibody against Set9 diluted 1:1,000 in TBS-Tween containing 5% skimmed milk. A molecular weight marker (in kDa) is shown on the left; the location of the protein of interest is indicated on the right.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blotting (1:1,000)
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Set9 antibody: human Set9 (SET domain containing (lysine methyltransferase) 9), using a recombinant protein.
• Concentration: lot specific
• Purification: Whole antiserum from rabbit containing 0.05% azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: SET domain containing lysine methyltransferase 7
• Database Link:
  NP_085151
  Entrez Gene 80854 Human
  UniProt ID Q8WTS6
• Background: Set9 (UniProtKB/Swiss-Prot entry Q8WTS6) is a histone methyltransferase which specifically methylates lysine 4 of histone H3 being a specific tag for epigenetic transcriptional activation. Further, methylation of histone H3K4 by Set9 precludes deacetylation of H3 by the NuRD complex and impairs Suv39h1-mediated methylation of H3K9. Set9 also methylates the tumor suppressor p53 at lysine 372, thereby enhancing its stability. It contains a SET domain but lacks the pre- and post-SET domains.).
• Synonyms: 9; KMT7; SET7; SET9

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Lysine degradation