KMT5A Rabbit Polyclonal Antibody

CAT#: TA347289

Rabbit Polyclonal SETD8 Antibody

Product Images

WB was performed on nuclear extracts from HeLa cells (HeLa NE, 20 ug) using the antibody against SETD8 diluted 1:1000 in TBS-Tween containing 5% skimmed milk. The molecular weight marker (in kDa) is shown on the right; the location of the protein of interest is indicated by an arrow.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blotting (1:1,000)
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-SETD8 antibody: human SETD8 (SET domain containing 8), using the full length protein containing a Flag-tagged N-terminus and a His-tagged C terminus.
• Concentration: lot specific
• Purification: Protein G purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: lysine methyltransferase 5A
• Database Link:
  NP_065115
  Entrez Gene 67956 MouseEntrez Gene 387893 Human
  UniProt ID Q9NQR1
• Background: SETD8 (UniProtKB/Swiss-Prot entry Q9NQR1) is a histone methyl transferase that specifically monomethylates 'Lys-20' of histone H4. This histone modification represents a specific tag for epigenetic transcriptional repression en is enriched during mitosis. SETD8 may also play a role in maintaining silent chromatin by preventing the acetylation of the H4 tail.
• Synonyms: PR-Set7; SET07; SET8; SETD8

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Lysine degradation