Caveolin 1 (CAV1) Rabbit Polyclonal Antibody

CAT#: TA347350

Rabbit Polyclonal Anti-Caveolin-1 Antibody

Product Images

Western blot analysis on HuvEc cell lysate using Caveolin-1 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Caveolin-1 Antibody: A synthesized peptide derived from human Caveolin-1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25 kDa
• Gene Name: caveolin 1
• Database Link:
  NP_001744
  Entrez Gene 12389 MouseEntrez Gene 25404 RatEntrez Gene 857 Human
  UniProt ID Q03135
• Background: caveolin-1 May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Belongs to the caveolin family. Homooligomer. Interacts with GLIPR2, NOSTRIN, SNAP25 and syntaxin. Interacts with rotavirus A NSP4.
• Synonyms: BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21
• Note: Caveolin-1 antibody detects endogenous levels of total Caveolin-1

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Focal adhesion, Viral myocarditis