Dysferlin (DYSF) Rabbit Polyclonal Antibody

CAT#: TA347372

Rabbit Polyclonal Anti-Dysferlin Antibody

Product Images

Western blot analysis on K562 cell lysate using Dysferlin Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Dysferlin Antibody: A synthesized peptide derived from human Dysferlin
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 240 kDa
• Gene Name: dysferlin
• Database Link:
  NP_001123927
  Entrez Gene 26903 MouseEntrez Gene 8291 Human
  UniProt ID O75923
• Background: DYSF Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Belongs to the ferlin family. Interacts with CACNA1S. Interacts with ANXA1; the interaction is Ca(2+)- and injury state-dependent.
• Synonyms: FER1L1; LGMD2B; MMD1
• Note: Dysferlin antibody detects endogenous levels of total Dysferlin

Reference Data

• Protein Families: Transmembrane