SCN1A Rabbit Polyclonal Antibody

CAT#: TA347473

Rabbit Polyclonal Anti-Sodium Channel-pan Antibody

Product Images

Western blot analysis on HuvEc cell lysate using Sodium Channel-pan Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Sodium Channel-pan Antibody: A synthesized peptide derived from human Sodium Channel-pan
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 230 kDa
• Gene Name: sodium voltage-gated channel alpha subunit 1
• Database Link:
  NP_001159435
  Entrez Gene 20265 MouseEntrez Gene 81574 RatEntrez Gene 6323 Human
  UniProt ID P35498
• Background: SCN5A This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na(+) channel isoform.
• Synonyms: EIEE6; FEB3; FEB3A; FHM3; GEFSP2; HBSCI; NAC1; Nav1.1; SCN1; SMEI
• Note: Sodium Channel-pan antibody detects endogenous levels of total Sodium Channel-pan

Reference Data

• Protein Families: Druggable Genome, Transmembrane