TIMP3 Rabbit Polyclonal Antibody

CAT#: TA347482

Rabbit Polyclonal Anti-TIMP3 Antibody

Product Images

Western blot analysis on HuvEc cell lysate using TIMP3 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-TIMP3 Antibody: A synthesized peptide derived from human TIMP3
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25 kDa
• Gene Name: TIMP metallopeptidase inhibitor 3
• Database Link:
  NP_000353
  Entrez Gene 21859 MouseEntrez Gene 25358 RatEntrez Gene 7078 Human
  UniProt ID P35625
• Background: TIMP3 Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP1, MMP2, MMP3, MMP7, MMP9, MMP13, MMP14 and MMP15.
• Synonyms: HSMRK222; K222; K222TA2; SFD
• Note: TIMP3 antibody detects endogenous levels of total TIMP3

Reference Data

• Protein Families: Druggable Genome, Secreted Protein