EDD (UBR5) Rabbit Polyclonal Antibody

CAT#: TA347485

Rabbit Polyclonal Anti-EDD Antibody

Product Images

Western blot analysis on A549 cell lysate using EDD Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-EDD Antibody: A synthesized peptide derived from human EDD
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 309 kDa
• Gene Name: ubiquitin protein ligase E3 component n-recognin 5
• Database Link:
  NP_001269802
  Entrez Gene 70790 MouseEntrez Gene 51366 Human
  UniProt ID O95071
• Background: UBR5 E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
• Synonyms: DD5; EDD; EDD1; HYD
• Note: EDD antibody detects endogenous levels of total EDD

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis