XPA Rabbit Polyclonal Antibody

CAT#: TA347506

Rabbit Polyclonal Anti-XPA Antibody

Product Images

Western blot analysis on COLO205 cell lysate using XPA Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-XPA Antibody: A synthesized peptide derived from human XPA
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 40 kDa
• Gene Name: XPA, DNA damage recognition and repair factor
• Database Link:
  NP_000371
  Entrez Gene 22590 MouseEntrez Gene 7507 Human
  UniProt ID P23025
• Background: XPA Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.
• Synonyms: XP1; XPAC
• Note: XPA antibody detects endogenous levels of total XPA

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Nucleotide excision repair