TIF1 alpha (TRIM24) Rabbit Polyclonal Antibody

CAT#: TA347529

Rabbit Polyclonal Anti-TRIM24 Antibody

Product Images

Western blot analysis on Jurkat and K562 cell lysate using TRIM24 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-TRIM24 Antibody: A synthesized peptide derived from human TRIM24
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 117 kDa
• Gene Name: tripartite motif containing 24
• Database Link:
  NP_003843
  Entrez Gene 21848 MouseEntrez Gene 8805 Human
  UniProt ID O15164
• Background: TRIM24 an atypical protein kinase that functions as a transcriptional coactivator. Originally identified as a mammalian protein that enhances the AF-2 activity of the retinoid X receptor (RXR) in a yeast genetic screen. Binds to nuclear receptors in an agonist and AF2-activating domain (AF2-AD) dependent manner. Binding to the agonist-nuclear receptor complex induces its own hyperphosphorylation as well as the phosphorylation of TFIIEa, TAFII28, and TAFII55.
• Synonyms: hTIF1; PTC6; RNF82; TF1A; TIF1; TIF1A; TIF1ALPHA
• Note: TRIM24 antibody detects endogenous levels of total TRIM24

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transcription Factors