Prothrombin (F2) Rabbit Polyclonal Antibody

CAT#: TA347556

Rabbit Polyclonal Anti-THRB Antibody

Product Images

Western blot analysis on NIH-3T3 cell lysate using THRB Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-THRB Antibody: A synthesized peptide derived from human THRB
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 70 kDa
• Gene Name: coagulation factor II, thrombin
• Database Link:
  NP_000497
  Entrez Gene 14061 MouseEntrez Gene 29251 RatEntrez Gene 2147 Human
  UniProt ID P00734
• Background: prothrombin Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Belongs to the peptidase S1 family.
• Synonyms: PT; RPRGL2; THPH1
• Note: THRB antibody detects endogenous levels of total THRB

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein
• Protein Pathways: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Regulation of actin cytoskeleton