SMAD4 Rabbit Polyclonal Antibody

CAT#: TA347566

Rabbit Polyclonal Anti-Smad4 Antibody

Product Images

Western blot analysis on HeLa cell lysate using Smad4 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:3000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Smad4 Antibody: A synthesized peptide derived from human Smad4
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Affinity-chromatography
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 60 kDa
• Gene Name: SMAD family member 4
• Database Link:
  NP_005350
  Entrez Gene 17128 MouseEntrez Gene 50554 RatEntrez Gene 4089 Human
  UniProt ID Q13485
• Background: Smad4 transcription factor that mediates signal transduction by the transforming growth factor superfamily. The common smad (co-smad). Binds directly to consensus DNA-binding elements in the promoters of target genes. Promotes binding of the Smad2/Smad4/Fast-1 complex to DNA and provides an activation function required for Smad1 or Smad2 to stimulate transcription.
• Synonyms: DPC4; JIP; MADH4; MYHRS
• Note: Smad4 antibody detects endogenous levels of total Smad4

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Adherens junction, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Pancreatic cancer, Pathways in cancer, TGF-beta signaling pathway, Wnt signaling pathway